2020-09-24

Osteoconductive matrices and methods are provided that have one or more statins disposed therein. The matrices may be injected into a fracture site. The osteoconductive matrices provided allow for sustain release of the statin and facilitate bone formation and repair of the fracture site.

osteoconductive matrix. Autograft Harvest •Cancellous –Iliac crest (most common) •Anterior-taken from gluteus medius pillar •Posterior-taken from posterior The TheraFuze DBF® demineralized bone fibers in TheraCell's Fiber Matrix™ products are osteoinductive and osteoconductive and can be formed into a number of shapes. Demineralized cortical bone (DBM) powder is osteoinductive but its particulate nature renders it relatively non-osteoconductive. Features & Benefits • Osteoconductive: Natural bone matrix facilitates cell attachment and proliferation, and vascular in‑growth. • Structural: Cortical graft provides immediate structural support. • 100% Human Bone: Can remodel with a patient’s own tissue during the healing process.

Demineralized bone matrix (DBM) is an osteoconductive scaffold that is manufactured by acid extraction of allograft bone. While it provides no structural support, it contains noncollagenous proteins, osteoinductive growth factors, and type I collagen. osteoconductive properties6 • Osteoconductive matrix for cell attachment and proliferation7 • Pre-hydrated SymAlign grafts maintain compressive strength and increase This bone void filler provides an osteoconductive matrix and is available in a variety of sizes for varying surgical needs. Cancellous Chips available in two particle size ranges (1-4mm and 1-8mm) and four sizes: 5cc, 15cc, 30cc, and 60cc The present disclosure provides compositions useful in regeneration of connective tissue, particularly bone. The compositions comprise a continuous matrix formed of a polypeptide crosslinked with a second polymer and further comprise particles of a porous, osteoconductive material dispersed in the continuous matrix. TheraCell has developed a proprietary patented process to make fibers from demineralized bone and with those fibers, using textile processes to make a range of unique products. The TheraFuze DBF® demineralized bone fibers in TheraCell's Fiber Matrix™ products are osteoinductive and osteoconductive and can be formed into a number of shapes.

Osteoconductive Matrix PLUS (OCMP) is a blend of ground cancellous chips and demineralized cortical powder, all derived from the same donor. Learn More About OCMP PuraPly ® AM

Our GEM 21S combines a bioactive protein—highly purified rhPDGF-BB—with an osteoconductive matrix, ß-TCP. Learn More. GEM® ADAPT RCM. Collagen based resorbable dental membranes that meet the needs of various dental indications. Learn More. GEM® Bone Graft.

When hydrated with patient bone marrow aspirate (BMA), Alphatec Neocore becomes a complete bone graft, which possesses all the necessary components of … Demineralized bone matrix (DBM) is an osteoconductive and osteoinductive commercial biomaterial and approved medical device used in bone defects with a long track record of clinical use in diverse forms. Osteoconductive Properties of β-Tricalcium Phosphate Matrix, Polylactic and Polyglycolic Acid Gel, and Calcium Phosphate Cement in Bone Defects. Journal of Craniofacial Surgery, 2012. Thallita Queiroz. Sônia Panzarini. Eloa Luvizuto. Rogério Margonar.

– Growth factors encourage mesenchymal cells to differentiate into osteoblastic lineages. May provide osteoconduction, osteoinduction and osteogenesis; Drawbacks with advancing age; Can be used in combination with an osteoconductive matrix. Oct 2, 2015 The first patient surgical implantation of the Alphatec Neocore osteoconductive matrix, a synthetic scaffold for the regeneration of bone, was Bonus Synthetic Bone Graft Substitute granules are resorbable, osteoconductive matrices consisting of a thin, 2–10 micron layer of hydroxyapatite over a The requirement is for an ideal bone replacement which is osteoconductive, stem cells can immediately begin to proliferate and lay down new bone matrix Provides osteoconductive matrix. • Approximately equal amounts of crushed cortical and crushed cancellous. • Offered in two particle size ranges: 1-4mm and 1- The TheraFuze DBF® demineralized bone fibers in TheraCell's Fiber Matrix™ products are osteoinductive and osteoconductive and can be formed into a Demineralized bone matrix (DBM) is allograft bone that has had the inorganic mineral removed This will depend on the osteoconductive, osteoinductive and osteogenic capabilities of the graft. Currently, autograft bone harvested from th Feb 17, 2012 Order versus Disorder: in vivo bone formation within osteoconductive Mature osteoblasts responsible for bone matrix deposition were lining Bone conduction, or osteoconduction, is a bone matrix that provides bones with the materials they need to remain strong. Living bone cells are responsible for Nasal Reconstruction Using an Osteoconductive.
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osteoconductive matrix. Autograft Harvest •Cancellous –Iliac crest (most common) •Anterior-taken from gluteus medius pillar •Posterior-taken from posterior BIO 4® is a viable bone matrix containing endogenous bone forming cells including mesenchymal stem cells, osteoprogenitor cells, osteoblasts, osteoinductive and angiogenic growth factors.

True to its name and as an acid-extracted organic matrix from human bone sources, DBM retains much of the proteinaceous components native to bone, with small amounts of calcium-based solids, inorganic phosphates and some trace cell debris. Ideally, the scaffold should facilitate cell infiltration, matrix deposition, and cell attachment and consist of osteoconductive materials such as bone protein and hydroxyapatite.
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Osteoconductive Matrix Plus (OCMP) is a blend of ground cancellous chips and demineralized cortical powder derived from the same donor with natural osteoconductive and osteoinductive properties. Osteoconductive Matrix Plus offers natural osteoconductive and osteoinductive potential and provides superior handling characteristics for bone fusion

biocompatible, bioactive, osteoconductive, non-toxic, non-inflammatory and in drug delivery and tissue engineering; polymer matrix mediated synthesis of of biomaterials, such as, biocompatible, bioactive, osteoconductive, non-toxic, in drug delivery and tissue engineering; polymer matrix mediated synthesis of DBM, Demineralized Bone Matrix. DFDBA, Demineralized ECM, Extracellular Matrix. FVL, Factor V Leiden Osteochondral grafting.

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Technical Specifications • 11mm anterior-posterior depth • 14mm medial-lateral width • 5-10mm heights • Parallel Clincial Applications • Anterior Cervical Fusion Product Features • Preservon treated for fully hydrated ambient temperature storage • Provides an osteoconductive matrix for incorporation • Pre-sized for convenience and intraoperative efficiency • Processed with

Alphatec Neocore Osteoconductive Matrix is a synthetic scaffold that is designed to provide an effective core environment for bone growth. When hydrated with patient bone marrow aspirate (BMA), Alphatec Neocore becomes a complete bone graft, which possesses all the necessary components of bone growth.

An Osteoconductive Matrix. Ousia bioXEN is a naturally sourced bovine bone mineral. The unique manufacturing process of bioXEN results in a bone grafting

GEM® Bone Graft. Bone marrow which contains osteoprogenitor cells could potentiate the osteoinductive and osteoconductive properties of demineralized bone matrix. This study tested the ability of demineralized bone matrix with and without bone marrow to bridge large segmental defects, and evaluated the results both radiographically and biomechanically as compared to autogenous (isogeneic) cancellous bone … EXPONENT features an osteoconductive matrix with osteoinductive potential that provides a natural scaffold for cellular ingrowth and revascularization. EXPONENT has the osteoconductive ability to grow bone as fully characterized in an in vivo rabbit spinal model.

However due to lower donor sites availability, repeated surgeries, transmission of diseases, and cost involved in autograft and allograft [44,45] procedures, there is a need for the development of alternative materials in the form of bone tissue engineering. PlatFORM™ CM Osteoconductive Collagen Mineral Bone Graft Matrix Highly Purified Carbonate Apatite Mineral Superior to ß-tricalciumphosphate (ß-TCP) and hydroxyapatite (HA) as a bioresorbable bone graft substitute 1 Resorption, remodeling and structure analogous to human bone 2 osteoconductive matrix for the ingrowth of bone cells and blood vessels.